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They then used laser scanning photo-stimulation to map the connections between subplate neurons in the brains of mouse pups. A week after being given birth, the mice that received VPA exhibited patterns of hyperconnected subplate neurons and there were too many connections in the brain.

On the other hand, mouse pups that did not receive VPA showed normal connections in their developing cerebral cortex.

After 10 days, researchers found that the hyperconnected subplate neurons among VPA-dosed mouse pups became increasingly widespread and homogenous.

– See more at: http://imotortimes.local/articles/195509/20170201/autism-may-begin-during-early-brain-development-mice-study-shows.htm#sthash.3y3eAmZ8.dpuf 


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