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The guidance, issued on May 25 in a 38-page blueprint, reflects growing official concern that attackers are using generative AI, large language models and autonomous tools to discover exposed systems, weaponise flaws, craft phishing lures and scale malware operations faster than conventional security programmes can respond. The document places rapid remediation, continuous monitoring and exposure reduction at the centre of enterprise cyber defence.

CERT-In’s most stringent timeline applies to known exploited vulnerabilities affecting internet-facing and critical systems, including applications, identity platforms, cloud assets, APIs, operational technology and systems supporting essential business functions. Organisations are advised to patch, mitigate or isolate such weaknesses within 12 hours where feasible. Critical externally exposed vulnerabilities should be addressed within one day, while known exploited flaws inside internal systems should be fixed within one day unless compensating controls are implemented and documented.

The blueprint also recommends that critical internal vulnerabilities affecting high-value systems be remediated within three days, and high-severity vulnerabilities within five days based on risk prioritisation. Where patches are unavailable, organisations are expected to use temporary protections such as isolation, access restrictions, web application firewalls, API shields, feature disabling and enhanced monitoring until permanent fixes are deployed.

The directive signals a shift from audit-driven cybersecurity to continuous exposure management. CERT-In has warned that organisations can no longer depend on periodic assessments or reactive incident response when automated tools can identify weak credentials, misconfigured systems, insecure APIs and vulnerable internet-facing services at machine speed. The approach requires security teams to maintain live inventories of assets, prioritise exposed systems and test whether controls work under attack conditions.

AI is changing both sides of the cyber equation. Attackers can use it to automate reconnaissance, write exploit code, refine phishing messages, generate synthetic identities and adapt malicious software. Defenders are being pushed to use similar capabilities for anomaly detection, threat hunting, automated triage and faster containment. The risk, however, is that poorly governed AI systems can themselves become attack surfaces through prompt injection, data leakage, model manipulation, poisoned training data, model theft and compromised orchestration pipelines.

The guidance gives particular weight to organisations operating in banking, financial services, telecom, healthcare, government, energy, transport, cloud services and other critical infrastructure-linked sectors. These environments often rely on interconnected digital systems, third-party software, outsourced technology providers and legacy platforms, creating wider exposure when a single flaw is weaponised quickly.

Global breach data has reinforced the urgency behind faster patching. Software vulnerability exploitation has overtaken stolen credentials as a leading breach entry point in major datasets, while ransomware remains a high-impact threat. Security teams also face growing pressure from supply-chain compromise, shadow AI usage, cloud misconfiguration and business email compromise. Unauthorised use of public AI tools has become a data governance issue as employees may upload source code, business documents, credentials or customer information into platforms outside corporate oversight.

CERT-In’s blueprint calls for a zero-trust approach, least-privilege access, layered controls and secure-by-design practices across applications, infrastructure and AI workflows. It urges organisations to maintain visibility into AI deployments, restrict sensitive data uploads to public AI platforms, log AI activity, conduct adversarial testing and keep human approval for critical autonomous actions.

Software supply-chain visibility is another major focus. Organisations are encouraged to use software bills of materials and related inventories for AI models, cryptographic assets and hardware components to understand dependencies, validate provenance and coordinate remediation when vulnerabilities emerge in third-party products.

The new expectations build on India’s existing cyber incident reporting framework, under which specified cyber incidents must be reported to CERT-In within six hours. The latest blueprint does not merely extend compliance obligations; it raises operational expectations for boards, chief information security officers and technology vendors by linking resilience to the speed of response.

Smaller organisations may struggle with the 12-hour benchmark because patch testing, downtime concerns, legacy dependencies and staffing shortages often slow remediation. The guidance therefore recognises feasible mitigation as part of the response, but it also makes clear that unmanaged exposure is no longer acceptable when attackers can exploit public-facing weaknesses within hours.

Another significant step towards the success of ICVAX®

HONG KONG SAR – Media OutReach Newswire – 27 May 2026 – Immuno Cure Group (“Immuno Cure“), headquartered at Hong Kong Science Park, is pleased to announce the inauguration of the research facility for its HIV therapeutic DNA vaccine (“ICVAX^®“) at the Center of International Innovation for Technology and Science (“CIITS”) located in Hetao, Shenzhen. The facility aims for the development and application of key technologies for the clinical research and commercialization of Immuno Cure’s ICVAX^®. ICVAX^® is developed by Immuno Cure with the aim of achieving antiretroviral therapy (“ART“)-free functional cure for HIV infection. This project is carried out in collaboration with Prof. Zhiwei CHEN, the Founding Director of the AIDS Institute of Li Ka Shing Faculty of Medicine, the University of Hong Kong (“HKU AIDS Institute“), and Prof. Hongzhou LU, President of the Third People’s Hospital of Shenzhen, in the capacity as advisors.

CIITS is a national-level achievement transformation platform co-built by Guangdong Province, Shenzhen Municipality, and Tsinghua University, and is located at the Hetao Shenzhen-Hong Kong Science and Technology Innovation Co-operation Zone (“Hetao Co-operation Zone“). It is committed to building a world’s leading major technological innovation and industrialization platform with a global perspective. It focuses on key tracks including biomedicine, high-performance materials, and artificial intelligence (AI). It aims to aggregate global innovation resources, connect with leading enterprises, and conduct organized scientific research and achievement transformation to address national major strategic needs.

Since AIDS was first identified in 1981, 40.8 million people have died from HIV infection, with over 44.1 million people living with HIV globally. While antiretroviral therapy can effectively control HIV replication, it cannot cure the disease, highlighting the critical need for immunotherapies. Designed to enhance the host’s immune response, immunotherapies aim to achieve sustained viral control without lifelong ART, ultimately leading to complete viral suppression and functional cure. Immuno Cure’s proprietary innovative HIV therapeutic DNA vaccine, ICVAX^®, induces broad-spectrum, polyfunctional virus-specific T cells to achieve the ultimate goal of ART-free functional cure of HIV infection.

Immuno Cure completed the first-in-human Phase I clinical trial of ICVAX^® in November 2024, demonstrating excellent safety and promising immunogenicity. Two multi-center Phase II clinical trials—randomized, double-blind, and placebo-controlled—are scheduled to launch in Q2-2026 to evaluate the vaccine’s mechanism of action and efficacy. The trials will be conducted at Prince of Wales Hospital in Hong Kong, as well as eight top-tier hospitals in China, including the Shenzhen Third People’s Hospital, Beijing Ditan Hospital Affiliated to Capital Medical University, Beijing Youan Hospital affiliated to Capital Medical University, the Eighth People’s Hospital of Guangzhou, the Second People’s Hospital of Tianjin, the Sixth People’s Hospital of Zhengzhou, Chengdu Public Health Clinical Medical Center, and Chongqing Public Health Medical Center.

Notably, standardized testing systems for evaluating immunological and virological indicators are crucial for HIV vaccine clinical trials. However, the lack of domestic standard operating procedures (SOPs) for infectious samples in clinical trials hinders the clinical development and regulatory approval of novel infectious disease therapies like ICVAX^®. The mission of this research facility at CIITS is to establish an internationally aligned standardized clinical testing system for T-cell immunogenicity and viral reservoirs, as well as identify core biomarkers associated with vaccine efficacy — filling a domestic technical gap. Immuno Cure will offer the ICVAX^® Phase II clinical trial to facilitate the development of this standardized precision testing method for clinical sample analysis.

Dr. Xia JIN, CEO of Immuno Cure, stated, “I am delighted to be appointed to lead this key project of CIITS. I would also like to thank CIITS for the fully fitted modern laboratory space and the RMB10.0m funding support for this 2-year initial phase. My whole scientific team is committed to contributing diligently to the success of this project. I have no doubt that the development of a standardised testing regime would not only enhance the quality of our clinical trials for ICVAX^® but would also eventually be adopted as industry and national standards for the clinical translation of medicine for HIV/AIDS and other infectious diseases.

Renchen LIU, Executive Deputy Dean of Research Institute of Tsinghua University in Shenzhen and Director of CIITS, stated, “Warmest congratulations on the inauguration of the research facility for ICVAX^® at the CIITS. In the future, CIITS will continue to leverage its platform resources to implement full-chain incubation services. Project managers will provide service support throughout the entire project period, ensuring the smooth progress of the project through resource integration, talent recruitment and development, clinical collaboration, and achievement transformation. These efforts will safeguard the steady progress of the project.”

As the project advances, Immuno Cure’s ICVAX^® is positioned to become the world’s first therapeutic DNA vaccine to deliver an ART-free functional cure for HIV infection, bringing new hope to people currently living with HIV. In parallel, the standardized testing platform and collaborative innovation model developed through this effort will provide a scalable, replicable blueprint for R&D of novel therapies targeting other major infectious diseases. Together, these outcomes will strengthen the global competitiveness of biomedicine development in GBA and contribute to the development of national biosecurity capabilities and a more resilient public health system.

Hashtag: #ImmunoCure

https://immunocure.hk
https://www.linkedin.com/company/immuno-cure

The issuer is solely responsible for the content of this announcement.

About the Center of International Innovation for Technology and Science (“CIITS”)

Center of International Innovation for Technology and Science (CIITS), as the international headquarter of the Greater Bay Area National Center of Technology Innovation (GBA NCTI), is operated by Research Institute of Tsinghua University in Shenzhen (RITS). CIITS actively promotes the commercialization of technology and scientific advances with overseas and domestic innovation institutions and teams, as well as industry partners, focusing on areas such as biomedicine, advanced materials and artificial intelligence.

To learn more about CIITS, please follow the WeChat official account: gh_425f503135d5

About Immuno Cure

Immuno Cure is a clinical-stage biotechnology group headquartered at Hong Kong Science Park. Immuno Cure is committed to the R&D of innovative DNA vaccines and antibody immunotherapies for infectious diseases, inflammations, and cancers. Immuno Cure possesses two technologies: the “PD-1 Enhanced DNA Vaccine Platform” and the “Anti-Δ42PD1 Antibody”.

To learn more about Immuno Cure, please visit: www.immunocure.hk

The arrangement makes BlockShoals the approved local intermediary under the SEC’s StratBox framework, while Binance supplies technology, security systems, operational support and compliance expertise developed across regulated markets. The sandbox phase is expected to begin in the second half of 2026 and run for at least two years, giving regulators direct oversight of product testing before any wider rollout to users.

The move marks a notable shift in Binance’s strategy in the Philippines. Rather than seeking to restore access through an offshore model, the exchange is now pursuing market participation through a domestic company operating under SEC supervision. BlockShoals, a Philippine-incorporated fintech firm, secured approval under the crypto asset intermediary framework after a multi-year process involving regulatory conditions, compliance checks and investor-protection requirements.

Binance’s online presence in the Philippines was blocked in 2024 after the SEC said the platform had offered investment and trading services without the necessary licence. The regulator had warned the public about the exchange in November 2023, then moved to restrict website access through telecommunications authorities the following year. The action became one of the clearest signals that Manila intended to bring offshore digital-asset platforms under local rules.

That enforcement drive has since widened. The SEC’s crypto-asset service provider rules, issued in 2025, require firms serving Philippine users to register, maintain sufficient capital, observe marketing standards, and meet operational and reporting obligations. The framework is intended to protect retail investors while allowing controlled innovation in a market where crypto use remains high by regional and global standards.

The Philippines ranked ninth in the 2025 global crypto adoption index, reflecting strong activity across retail centralised services and digital-asset platforms. Usage has been driven by a young, mobile-first population, remittance demand, online work, gaming-linked crypto activity and a broad appetite for alternative financial products. That adoption has also heightened regulatory concern over fraud, weak disclosures, market volatility and the risks of foreign platforms serving users without domestic accountability.

Seker, Binance’s head of Asia-Pacific, described the Philippines as one of Southeast Asia’s most dynamic digital economies, saying frameworks such as StratBox create a channel for regulators and industry participants to work together while maintaining user protection and market integrity. The company has presented the BlockShoals partnership as part of a compliance-first approach rather than a conventional market relaunch.

BlockShoals has framed its role around local accountability. A company representative said the partnership was an opportunity to show that global digital-asset platforms and domestic regulatory frameworks could operate constructively together, adding that the firm would work under direct SEC supervision while building a secure platform for users.

The sandbox structure gives the SEC room to monitor how products are configured, how customer onboarding is handled, how risks are disclosed, and how safeguards such as know-your-customer checks, anti-money-laundering controls and transaction monitoring are applied. It also gives Binance a pathway to rebuild trust after a period in which its Philippine operations were defined by access restrictions and licensing concerns.

The Philippine approach mirrors a broader shift across Asia, where regulators are moving away from informal tolerance of offshore crypto activity and towards domestic licensing regimes. Singapore, Hong Kong, Thailand, Indonesia and Japan have tightened rules for exchanges, stablecoin activity, custody, marketing and investor suitability. The result is a more fragmented operating environment for global platforms, with access increasingly dependent on local registration, capital commitments and regulator-facing governance.

For Binance, the Philippine partnership carries strategic value beyond one market. The exchange has spent the past several years seeking to repair relations with regulators after facing scrutiny in multiple jurisdictions. A successful sandbox test in Manila would support its argument that global crypto platforms can adapt to local rules through partnerships, product controls and supervised deployment.

The renewed memorandum of understanding was signed on 25 May by Rear Admiral Saif bin Nasser Al Rahbi, Commander of the Royal Navy of Oman and Chairman of the Maritime Security Committee, and G. V. Srinivas, India’s Ambassador to the Sultanate of Oman. Oman was represented by the Maritime Security Centre, underlining the agreement’s operational focus on maritime safety, information-sharing and cooperation at sea.

The renewal keeps in place a mechanism that has gained importance as shipping routes through the Arabian Sea, Gulf of Oman and Strait of Hormuz face heightened risks from regional conflict, trafficking networks, drone threats, piracy-linked activity and disruptions to commercial navigation. For both countries, maritime security is tied not only to defence cooperation but also to energy flows, trade resilience and the protection of expatriate and commercial links across the Gulf.

The agreement aims to sustain joint cooperation and facilitate the exchange of expertise in maritime security, with the stated objective of contributing to the safety and security of maritime navigation. Its scope fits into a wider pattern of bilateral defence engagement involving naval interaction, coast guard cooperation, training, port calls, high-level meetings and operational contact between maritime agencies.

Oman’s location gives the pact strategic weight. The Sultanate sits close to the Strait of Hormuz, through which a significant share of the world’s seaborne oil trade passes, and faces the Arabian Sea, a route connecting the Gulf with East Africa, South Asia and the wider Indo-Pacific. India’s energy imports, diaspora links and commercial shipping make stability in these waters a central security interest.

The renewed document also reflects a continuity in defence ties that have developed through structured mechanisms over two decades. India and Oman have maintained regular military cooperation, including joint committee meetings, staff-level exchanges and service-to-service engagement. Earlier maritime arrangements between the two sides covered cooperation against crimes at sea, including piracy, armed robbery, arms trafficking, drug smuggling, illegal immigration and people-smuggling by sea.

Coast guard engagement has become a practical arm of that relationship. The Indian Coast Guard and Royal Oman Police Coast Guard have used high-level meetings to discuss capacity-building, cross-ship visits, the Sea Rider programme, pollution-reporting links and cooperation against transnational illegal activity at sea. Such measures are aimed at creating working-level familiarity before crises emerge, particularly in areas where law-enforcement, search-and-rescue and environmental response overlap.

The agreement comes as maritime security has moved higher on the regional agenda. Attacks on merchant vessels in and around the Red Sea, tensions linked to the Israel-Gaza war, risks around Iran-linked flashpoints and the vulnerability of energy shipping have pushed Gulf and Indian Ocean states to strengthen coordination. Oman has also positioned itself as a diplomatic and maritime actor with an interest in keeping sea lanes open while maintaining dialogue with multiple regional powers.

For India, Oman remains one of its closest defence partners in the Gulf. Access, trust and geography make the relationship important for deployments, evacuation contingencies, anti-piracy coordination and wider maritime domain awareness. Oman has historically provided India with a reliable western Indian Ocean partner, while Muscat benefits from deeper technical, training and operational interaction with a major naval power.

The security renewal also sits alongside a growing economic relationship. Bilateral trade has crossed the $10 billion mark, and the two countries signed a comprehensive economic partnership agreement in December 2025 to expand market access for goods and services. The trade pact gave exports from India zero-duty access across most Omani tariff lines, while New Delhi agreed tariff reductions covering a large share of imports from Oman by value.

That economic backdrop makes maritime security more than a defence concern. Smooth shipping flows affect energy supplies, fertilisers, minerals, food products, pharmaceuticals, textiles and engineering goods. Oman’s ports and logistics infrastructure are also relevant to India’s westward trade links, particularly as supply chains adjust to geopolitical tensions and route disruptions.

The renewed memorandum is expected to support more sustained institutional contact between the two sides rather than a one-off diplomatic gesture. Its emphasis on expertise-sharing suggests cooperation may cover surveillance practices, response protocols, training modules, information exchange and coordination against illegal activities at sea. It also offers a framework for strengthening maritime navigation safety at a time when commercial vessels increasingly require layered protection across contested waters.

By Nitya Chakraborty With the U.S. President Donald Trump himself downgrading the status of the four nation Quadrilateral Security Dialogue (QUAD), why is Indian government spending so much of its precious time on QUAD meetings? It is sheer wastage of time for the Prime Minister Narendra Modi as also Foreign Minister Dr. S Jaishankar. US […]

The article Trump Has Downgraded Status Of QUAD-India Should Not Waste Time On It appeared first on Latest India news, analysis and reports on Newspack by India Press Agency).

The agreement was signed on Tuesday during the Quad foreign ministers’ meeting in New Delhi, where External Affairs Minister S Jaishankar and US Secretary of State Marco Rubio held talks covering economic security, energy resilience and Indo-Pacific cooperation. The pact gives both countries a structured route to work together across the full minerals value chain, from exploration and extraction to refining and downstream industrial use.

Critical minerals and rare earth elements have become central to the global contest over clean-energy technologies, semiconductors, electric vehicles, defence systems, communications equipment and advanced manufacturing. For New Delhi, the agreement offers access to US capital, technology partnerships and supply-chain coordination at a time when domestic demand for lithium, cobalt, nickel, graphite, copper and rare earth magnets is expected to rise sharply.

China’s dominance remains the main strategic driver behind the pact. Beijing controls a large share of global rare earth refining and magnet production, giving it leverage over industries that depend on high-performance permanent magnets, battery inputs and specialised industrial materials. Export restrictions and licensing measures imposed by China on select critical minerals have added urgency to efforts by major economies to diversify sourcing and processing.

New Delhi’s gains could come in several layers. The first is supply security. India’s electronics, defence, renewable energy and electric mobility sectors need stable access to minerals that are often mined in one region and processed in another. A bilateral framework with Washington can help identify viable projects, link producers with manufacturers and create longer-term offtake arrangements that reduce price and availability shocks.

The second benefit lies in processing. India has mineral-bearing resources, a large manufacturing base and expanding demand, but it lacks sufficient refining and separation capacity for several high-value critical minerals. Collaboration with US companies and research institutions could support technology transfer, pilot processing facilities, environmental safeguards and recycling systems. That is particularly important because rare earth value chains are not only about mining; separation, purification and magnet-making often determine strategic control.

A third advantage is financing. Critical mineral projects are capital-intensive, slow to develop and vulnerable to volatile prices. The new framework is expected to encourage coordinated investment, risk-sharing and policy support. For India, this could help attract patient capital into mineral exploration, processing parks, recycling ventures and specialised manufacturing units linked to batteries, magnets and electronics.

The agreement also fits into New Delhi’s wider industrial strategy. The government has launched auctions for critical mineral blocks, expanded exploration and moved to build partnerships with resource-rich countries. State-backed and private companies have shown growing interest in lithium, rare earths and battery materials, while domestic manufacturers are seeking greater localisation of supply chains for electric vehicles, solar power, wind equipment and semiconductors.

Washington’s interest is equally clear. The US wants trusted partners that can help build alternatives to China-centred mineral flows. India offers scale, engineering capacity, a large market and geopolitical alignment through the Quad. A stronger minerals partnership can also support US efforts to diversify clean-energy and defence supply chains beyond a narrow group of suppliers.

The pact follows earlier India-US cooperation in technology, defence, semiconductors and clean energy. It also complements Quad-level initiatives designed to strengthen supply chains and energy security across the Indo-Pacific. Australia brings mining strength, Japan brings advanced materials and manufacturing capacity, the US brings capital and technology, and India brings market scale and industrial ambition.

Challenges remain substantial. New mining and processing projects often face long approval timelines, environmental scrutiny, land acquisition issues and high upfront costs. Rare earth separation involves complex chemistry and waste management concerns. Recycling can reduce dependence on fresh extraction, but collection systems and processing capacity remain underdeveloped. India will also need a skilled workforce, stable regulation and clear pricing signals to convert diplomatic agreements into viable industrial projects.

Commerce and Industry Minister Piyush Goyal’s visit to Ottawa and Toronto, accompanied by more than 100 business leaders, has added momentum to negotiations on a Comprehensive Economic Partnership Agreement, which both sides see as central to expanding market access, investment flows and supply-chain cooperation. The visit comes after a prolonged freeze in trade discussions caused by the diplomatic dispute that followed the 2023 killing of Sikh separatist Hardeep Singh Nijjar in British Columbia.

New Delhi and Ottawa are now working to rebuild trust through a structured commercial agenda covering energy, agriculture, critical minerals, technology, education and services. The scale of the business delegation travelling with Goyal underlines the attempt to shift the relationship from political caution to transaction-led engagement. A “Team Canada” delegation is expected to visit India later this year, signalling that both governments want to sustain ministerial and private-sector contact beyond formal negotiating rounds.

Bilateral trade remains below potential for two large economies with complementary strengths. Merchandise trade between the two countries stood at about $13.6 billion in 2025, with Canada exporting vegetables, mineral fuels, oils and wood pulp, while imports from India were led by precious stones and metals, machinery, pharmaceuticals and manufactured goods. Services trade, especially in technology, education, professional services and mobility-linked sectors, has grown into a significant part of the relationship.

The $50 billion target is ambitious but not beyond reach if negotiations produce tariff concessions, regulatory clarity and stronger investment protections. India is seeking reliable access to critical minerals, energy products, gas, fuel and agricultural inputs from Canada. Ottawa, for its part, sees India as a large growth market at a time when Canada is trying to diversify trade beyond its heavy dependence on the United States.

Energy is likely to become one of the pillars of the renewed partnership. Canada’s reserves of uranium, potash, natural gas and critical minerals fit India’s requirements for food security, clean energy expansion and industrial supply chains. Civil nuclear cooperation has returned to the agenda, with uranium supply discussions forming part of the broader effort to rebuild strategic confidence. India’s rising electricity demand and its plan to expand non-fossil energy capacity give Canada a commercial opening in nuclear fuel and related technologies.

Agriculture and fertilisers also carry strategic weight. Canada is a major supplier of potash, while India’s farm sector requires stable input supplies to support food production. Pulses have long been part of the trade basket, though pricing, phytosanitary rules and domestic market sensitivities have at times complicated flows. A broader agreement could provide more predictable rules, but both sides will have to manage farmer concerns and safeguard mechanisms carefully.

Technology and education offer another route to deeper engagement. Canada remains a major destination for students from India, while companies in both countries are exploring artificial intelligence, clean technology, fintech, cybersecurity and advanced manufacturing. Talent mobility will remain a sensitive but crucial component of any expanded economic relationship, especially as Canada adjusts immigration settings and India pushes for easier access for skilled professionals.

The political backdrop remains complex. Relations deteriorated sharply in 2023 after Canada alleged involvement by agents linked to New Delhi in Nijjar’s killing, an accusation India rejected. Diplomatic expulsions and a pause in trade talks followed, slowing a relationship that had already been marked by differences over separatist activism, security concerns and diaspora politics. The decision to restart CEPA negotiations reflects a pragmatic calculation that economic interests can create stabilising channels even when political trust is still being repaired.

Business groups on both sides are pressing for faster progress. Exporters want lower tariffs, simpler customs procedures and clearer standards rules. Investors are seeking safeguards, dispute-resolution mechanisms and sectoral openings. Canada’s pension funds and institutional investors already have exposure to infrastructure, real estate and financial assets in India, while companies from India are looking at Canadian opportunities in technology, mining, manufacturing and services.