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The Mach33: Physical AI Fashion Show, held on 28 May at Galaxy Robot Park in Gangdong District, was presented as more than a novelty catwalk. Galaxy Corporation framed the event as an experiment in coexistence, asking how people and robots might share cultural spaces rather than treating humanoids only as factory tools, laboratory platforms or service machines.

Each model appeared with a shorter humanoid counterpart, often wearing matching or complementary outfits. A tasselled blue Texan-style look, complete with a robot-sized cowboy hat, stood alongside retro silver outerwear, silky dresses fitted to rigid frames and space-age black trousers reminiscent of David Bowie’s 1970s stage style. The styling made the mechanical bodies appear less like exposed prototypes and more like performers entering a commercial entertainment format.

Galaxy Corporation founder and chief executive Choi Yong-ho said the company had realised that robots “need to wear clothes” and argued that robots, like people, should have distinct identities. The company designed the outfits and intends to launch them under the MACH 33 name by the end of the year, positioning robot fashion as a potential extension of its entertainment-technology business.

The event followed the opening phase of Galaxy Robot Park, a 16,500-square-metre venue in eastern Seoul designed around robot concerts, interactive shows, robotic portrait drawing, boxing-style demonstrations and visitor experiences. The park is part of Galaxy Corporation’s effort to create a new live-entertainment category built around “physical AI”, a term used to describe artificial intelligence moving from screens and software into embodied machines operating in shared human spaces.

Galaxy Corporation, known for managing cultural figures including G-Dragon, Taemin and actor Song Kang-ho, has been seeking to merge K-pop spectacle with robotics. Its robot performances have included choreographed dance routines, synchronised stage movement and plans for several shows a day. The company has said it wants to stage more than 1,000 robot performances annually and ultimately take robot-led shows beyond South Korea.

The robot models appeared to be Unitree G1 humanoids, a relatively low-cost platform made by Hangzhou-based Unitree Robotics. The G1 is widely used in demonstrations because of its compact size, balance control, range of motion and comparatively accessible pricing for developers and institutions. Its ability to walk, turn, gesture and respond to programmed choreography makes it suitable for controlled performances, though it remains far from a fully autonomous general-purpose worker.

The show also highlighted the gap between polished presentation and engineering reality. Humanoid robots are becoming more agile, but smooth movement in a runway setting still requires careful staging, reliable control systems and predictable conditions. Research into whole-body teleoperation, motion retargeting and autonomous loco-manipulation continues to point to unresolved challenges, including latency, balance recovery, hand dexterity, human-robot interaction and safe operation in crowded public spaces.

For South Korea’s entertainment sector, the Galaxy event fits a broader pattern of experimentation with virtual idols, AI-generated content, immersive fan platforms and digitally enhanced performances. K-pop’s visual emphasis makes it a natural testing ground for robotic spectacle, but the commercial test will be whether audiences view robot performers as compelling cultural products or as temporary curiosities.

Fashion offers Galaxy a softer route into that debate. Unlike industrial robotics, a runway show does not require humanoids to prove productivity. It asks whether machines can be styled, branded and given a visible role in popular culture. The clothes also conceal some of the awkwardness of exposed mechanical frames, making the robots appear less clinical and more theatrical.

The commercial stakes are growing. Forecasts for humanoid robotics vary widely, but major financial institutions and technology analysts expect the sector to expand sharply over the next two decades as costs fall and AI systems improve. Optimistic projections point to hundreds of millions, or even more than a billion, humanoids by 2050, though adoption is expected to move gradually as companies work through safety, reliability, regulation and public acceptance.

The Ministry of Energy and Mineral Resources is working with the Ministry of Agrarian Affairs and Spatial Planning, state electricity company PLN and other agencies to identify land, grid links and storage systems needed for the programme. About 24,000 hectares on Java Island have been earmarked for verification, with the authorities seeking to match project sites with transmission lines, PLN substations and battery storage capacity.

Deputy Energy and Mineral Resources Minister Yuliot Tanjung said the government’s first priority is to push ahead with an initial 17 GW phase, supported by around 33 GW of battery energy storage systems. The early phase is expected to test the country’s ability to turn a national target into bankable projects at scale, particularly in areas where land acquisition, grid connection and tariff design have slowed renewable energy investment.

The wider 100 GW plan is designed to reduce Indonesia’s reliance on diesel and gas-fired generation, particularly in regions where imported fuel and high operating costs have weighed on the state budget. Officials have estimated that converting fossil fuel-based generation to solar power combined with battery storage could cut electricity generation costs by up to Rp73.9 trillion, or about $4.18 billion, a year once implemented at scale.

The programme also reflects Jakarta’s attempt to close the gap between Indonesia’s large solar potential and its modest installed capacity. The country has abundant sunshine across its islands, yet solar has remained a small part of the electricity mix compared with coal, gas, hydro and geothermal power. Rooftop and utility-scale solar deployment has been constrained by regulatory uncertainty, procurement delays, grid limitations and the financial position of PLN.

Indonesia’s latest electricity supply plan for 2025-2034 calls for 69.5 GW of new generation capacity, with renewable energy making up a large share of future additions. Solar is expected to play a central role in that expansion, with PLN’s planning framework pointing to 17.1 GW of new solar capacity by 2034 alongside hydro, geothermal, wind and storage projects. The 100 GW programme goes beyond that planning baseline and signals a more aggressive policy push from President Prabowo Subianto’s administration.

A key feature of the solar strategy is its decentralised design. Earlier planning discussions have described a model that could combine large centralised solar plants with smaller village-level systems, many paired with batteries. Such an approach could help remote communities replace diesel generation, improve supply reliability and reduce exposure to fuel price volatility, while also creating demand for locally produced panels, batteries, inverters and grid equipment.

The proposed investment scale underlines the financing challenge. A $71.3 billion programme would require state support, PLN procurement commitments, private sector participation, concessional finance and possibly blended funding from climate-related investment platforms. Indonesia has already attracted international attention through its Just Energy Transition Partnership, but converting pledges into project-level funding has remained difficult, particularly because coal continues to dominate power generation and captive industrial power demand is rising.

Land availability will be another decisive issue. Java, the country’s most populous island and main electricity demand centre, offers stronger grid connectivity but also intense competition for land. The identification of 24,000 hectares is a first step rather than a final allocation, as each site must still pass verification covering ownership, spatial planning, environmental suitability and connection feasibility.

Grid readiness may prove equally important. Large volumes of intermittent solar power will require stronger transmission networks, flexible generation, storage systems and updated dispatch rules. Battery storage is central to the plan because solar output peaks during daylight hours while demand often rises in the evening. Without adequate storage and grid upgrades, high solar penetration could create curtailment risks and weaken project economics.

The programme could strengthen Indonesia’s industrial policy if it succeeds in building domestic solar manufacturing capacity. Officials have linked the plan to demand for locally produced panels, a move that could support factories, create jobs and reduce exposure to import barriers in global solar trade. The strategy comes as several countries seek to capture more of the clean energy supply chain, from polysilicon and wafers to modules and battery systems.

Indonesia’s energy transition remains complicated by its coal-heavy electricity system, long-term power purchase agreements and the need to provide affordable energy to households and industry. Coal plants still anchor baseload supply, while nickel processing and other industrial sectors have increased captive power demand. Those pressures make the solar programme both a climate policy instrument and an energy security strategy.

Work on floating solar projects, rooftop systems and village electrification schemes has already begun to build momentum. PLN’s Saguling floating solar project in West Java, scheduled for commercial operation in late 2026, is one of several projects intended to demonstrate technical and commercial viability. The larger 100 GW plan, however, will require faster procurement, clearer tariff rules and stronger coordination across ministries, PLN, regional governments and investors.

The unit sits under the president’s office and is evaluating AI start-ups globally, with long-serving executive Zhang Endong leading the effort. The move places investment activity closer to Sea’s top management at a time when the company is trying to convert its scale across Shopee, Garena and Monee into a stronger position in the next phase of consumer internet competition.

The new team is part of a wider internal reorganisation aimed at accelerating AI adoption across Sea’s businesses. Zhang is also involved in projects examining how the technology can be deployed inside the group, from product recommendations and seller tools to game development and financial services. A company spokesperson declined to comment on the investment unit.

The initiative follows a series of signals from chief executive Forrest Li that AI has become central to Sea’s long-term strategy. Li told investors last year that a trillion-dollar market capitalisation could be possible if the company doubled down on artificial intelligence and made the right calls. That ambition is now being tested against tougher operating conditions, heavier competition and investor scrutiny over margins.

Sea’s pivot comes as its core businesses remain sizeable but increasingly contested. Shopee continues to dominate e-commerce across South-east Asia, where price-led competition, live commerce, faster delivery expectations and merchant services have raised both growth potential and operating costs. Rivals including TikTok Shop, Lazada, Amazon and Rakuten are intensifying their own use of AI to personalise shopping, automate seller support and streamline logistics.

Artificial intelligence is already being built into Shopee’s customer and merchant systems. Its applications include recommendation engines, search improvements, advertising tools and seller assistance functions. The strategic logic is straightforward: more effective targeting can increase conversion, better seller tools can deepen merchant loyalty, and automated service functions can reduce costs across markets with different languages, payment habits and logistics infrastructure.

Sea has also expanded its partnership with Google to develop AI-powered tools across e-commerce and gaming. The companies are exploring an agentic shopping prototype for Shopee, designed to move beyond basic search and recommendation functions towards digital assistants capable of helping consumers complete tasks across the shopping journey. Garena is expected to use AI to improve game development productivity, an area where faster content cycles and lower development costs can carry significant commercial value.

Financial performance has given Sea room to invest, though not without pressure. First-quarter revenue rose 46.6 per cent year on year to US$7.1 billion, while gross profit increased 40.7 per cent to US$3.1 billion. Net income reached US$438.2 million, up 6.7 per cent, and adjusted EBITDA rose 9.3 per cent to US$1 billion. The figures showed continued momentum, but also reflected the cost of defending market share and expanding services.

Shopee delivered gross merchandise value of US$37.3 billion in the quarter, up 30.2 per cent from a year earlier, while gross orders climbed 29.3 per cent to 4 billion. Revenue from the e-commerce arm rose 45.1 per cent to US$5.1 billion, though adjusted EBITDA fell to US$223.2 million from US$264.4 million a year earlier, underlining the margin trade-off behind its expansion strategy.

Monee, Sea’s digital financial services unit, has become another pillar of growth. Revenue rose 57.8 per cent to US$1.2 billion, while consumer and small-business loans outstanding reached US$9.9 billion. Non-performing loans more than 90 days past due remained at 1.1 per cent, a key metric as the company expands credit services across emerging markets where risk controls are critical.

Garena, once Sea’s dominant profit engine, also showed stronger momentum. Bookings rose 20.1 per cent to US$931.4 million, while quarterly active users stood at 666.5 million. The unit remains anchored by Free Fire, but Sea’s AI push suggests management sees broader potential in development tools, content generation, player engagement and operational efficiency.

Sea’s AI Centre of Excellence in Singapore adds another layer to the strategy. The centre is intended to strengthen local AI capabilities, support enterprise adoption and develop talent in areas such as engineering, research and product development. Its launch aligns the company with Singapore’s broader ambition to become a regional AI hub and gives Sea a clearer institutional base for experimentation.

The investment team could give Sea access to external innovation at a time when start-ups are moving faster than large platforms in areas such as autonomous commerce, generative game design, fraud detection, credit scoring and AI-enabled logistics. The challenge will be distinguishing durable business models from inflated valuations in a crowded funding environment.

Investors will be watching whether Sea’s AI spending produces measurable gains in revenue growth, user engagement and margin improvement. The company has already shown that it can rebuild profitability after years of expansion-led losses. Its next test is whether AI can become more than an efficiency tool and help create the next major growth curve for one of South-east Asia’s most valuable technology groups.

A draft framework under consideration would expand the role of monitoring agencies, usually SEBI-registered credit rating firms, and give them a stronger channel to flag diversion, delays or non-cooperation in the deployment of funds raised through equity issues. The proposals cover initial public offerings, rights issues, preferential allotments and qualified institutional placements, widening the regulatory lens beyond conventional IPO scrutiny.

Central to the plan is a proposal to lower the threshold for mandatory monitoring of issue proceeds from ₹100 crore to ₹50 crore. That change would bring a larger number of mid-sized fundraisings under independent review, particularly at a time when companies are using public markets not only for expansion but also for debt repayment, acquisitions, working capital and general corporate purposes.

The proposed framework would also require monitoring agencies to report directly to stock exchanges, rather than depend mainly on issuers for the onward dissemination of their findings. This would mark a significant shift in the balance of responsibility, as exchanges would receive a clearer view of whether the stated objects of an issue match actual fund utilisation.

Companies that fail to cooperate with monitoring agencies could face penalties, including fines of ₹50,000 for each violation. The measure is intended to address a weakness in the current structure, where monitoring agencies review deployment but have limited power when issuers delay information, provide incomplete data or fail to explain deviations from stated plans.

SEBI’s initiative comes after a period of heavy fundraising through equity markets, followed by a more cautious phase shaped by global risk aversion, pressure on domestic stocks and foreign portfolio outflows. Large companies and new-age firms have kept IPO plans alive, but several issuers have deferred listings as valuations became harder to defend. The regulator’s draft reflects a view that investor confidence depends not only on disclosure before fundraising but also on verifiable use of proceeds after capital is raised.

Under existing rules, companies raising equity funds must disclose the objects of the issue in offer documents and provide periodic updates on utilisation. Monitoring agencies submit reports on whether the proceeds are being used as promised. These reports are placed before audit committees and submitted to stock exchanges, but the enforcement burden largely remains with the issuer and the regulator.

The proposed changes would make monitoring more active and less dependent on company-led disclosure. Rating firms would be expected to examine bank statements, payment trails, board approvals and project progress more closely. They may also need to identify whether funds have been parked for long periods, shifted to purposes not approved by investors, or routed through related-party arrangements.

For investors, the changes could improve visibility over post-issue conduct, especially in cases where companies raise money for broad purposes and later alter business plans. Fund diversion has long been a concern in equity markets because public shareholders bear the risk when proceeds are used for objectives that differ materially from those advertised during the fundraising process.

For issuers, the proposals may raise compliance costs and increase documentation burdens. Smaller companies crossing the proposed ₹50 crore threshold would have to engage monitoring agencies and respond to periodic queries. Market participants expect some pushback from companies that argue existing audit committee and exchange disclosure requirements already provide sufficient oversight.

The regulatory argument is that tougher monitoring could reduce the gap between promise and performance. When a company raises money to build capacity, buy assets or reduce debt, the market prices the issue partly on those declared plans. If funds are later diverted or left idle without adequate explanation, minority shareholders have limited ability to intervene.

Credit rating agencies would gain a more prominent governance role under the proposed structure. Their task would move beyond checking utilisation statements to becoming a stronger early-warning mechanism for exchanges and investors. That may also bring questions over capacity, liability and conflict management, since the same agencies operate across ratings, surveillance and advisory-linked functions.

SEBI has been refining capital-raising rules across public issues, preferential allotments, rights issues and qualified institutional placements as it seeks to balance ease of fundraising with protection for minority investors. The latest proposal fits into a broader regulatory push to make market access faster while demanding greater transparency after money is raised.

“Building on AECOM’s long-standing contribution to Hong Kong’s airport development and our partnership with AAHK since the 1990s, we helped deliver a world-class terminal that enhances connectivity and strengthens resilience, setting new benchmarks for aviation in a changing world,” said Dr. Johnny Cheuk, AECOM’s Hong Kong executive leader.

AECOM’s multi-disciplinary team brought together expertise in mega project management, engineering and passenger terminal design to deliver innovative, buildable solutions through phased construction, minimizing disruption within a live airport environment. A signature feature of T2 is its 63,000 m² ‘Feather Roof,’ supported by tree-like columns, combining architectural expression with operational performance. Leveraging multiple digital solutions such as BIM and Tekla, alongside phased modular construction significantly enhanced the precision, safety and delivery efficiency of this iconic roof structure.

Supporting HKIA’s pledge to become the world’s greenest airport, sustainability is embedded throughout the project. Key measures include implementing a high-performance façade that enhances thermal efficiency, natural daylighting and acoustic comfort. AECOM also helped define embodied carbon quantification standards at the outset of this project more than a decade ago. These are complemented by energy-efficient building services that reduce overall energy consumption, contributing to the award of BEAM Plus Provisional Platinum rating — the highest qualification level recognized by the Hong Kong Green Building Council (HKGBC).

Hashtag: #AECOM #Aviation #Terminal2

https://aecom.com

The issuer is solely responsible for the content of this announcement.

About AECOM

AECOM is the global infrastructure leader, committed to delivering a better world. As a trusted professional services firm powered by deep technical abilities, we solve our clients’ complex challenges in water, environment, energy, transportation and buildings. Our teams partner with public- and private-sector clients to create innovative, sustainable and resilient solutions throughout the project lifecycle – from advisory, planning, design and engineering to program and construction management. AECOM is a Fortune 500 firm that had revenue of US$16.1 billion in fiscal year 2025. Learn more at aecom.com.

Prudent Risk Management Yields Solid Outcomes metrics, Core Pawn Business Demonstrates Resilient Growth with Proposed Final Dividend of HK$1.15 cents per share

Results Highlights:

• Profit for the year attributable to shareholders increased by approximately 47.8% YoY to approximately HK$82.6 million
• Net profit margin increased by approximately 16.2 p.p. YoY to approximately 50.2%
• Impairment losses recognized on loan receivables decreased by approximately 72.6% YoY to HK$12.7 million
• Revenue from pawn loan business increased by approximately 12.9% YoY to approximately HK$98.6 million
• Proposed final dividend of HK$1.15 cents per share

HONG KONG SAR – Media OutReach – 27 May 2026 – The board of directors of Oi Wah Pawnshop Credit Holdings Limited (HKEx stock code: 1319.HK, the “Group” or “Oi Wah”) announced its annual results and its financial position. For the year ended 28 February 2026 (“FY2026“), the Group recorded revenue of approximately HK$164.4 million. Profit attributable to shareholders of the Company reached approximately HK$82.6 million, representing an increase of 47.8% compared to the year ended 28 February 2025 (“FY2025“). During the year, net interest margin expanded to approximately 17.2%.

As of 28 February 2026, the cash and cash equivalents (net of bank overdraft) amounted to approximately HK$376.9 million, representing a substantial increase of approximately 74.8% YoY. The net assets increased to approximately HK$1,155.7 million. Concurrently, the gearing ratio dropped to 4.1%. During the year, the earnings per share increased by approximately 48.3% YoY to HK 4.3 cents. The Board of Directors recommends a final dividend of HK 1.15 cents per share.

BUSINESS REVIEW

Mortgage loan business

In FY2026, the economy entered a phase of gradual recovery, leading to a steady resurgence in financing demand. The revenue from the mortgage loan business was approximately HK$65.8 million and accounted for approximately 40.0% of the Group’s total revenue during the year. The gross mortgage loan receivables were approximately HK$612.5 million as at 28 February 2026. During the year, net interest margin of the mortgage loan business was approximately 10.1%.

In FY2026, the Group maintained a disciplined and risk-sensitive approach in its lending activities. While we observed an encouraging stabilization in the residential property market, the Group exercised intensified vigilance toward the commercial and industrial sectors due to persistent supply overhangs and valuation pressures. Our underwriting strategy remained focused on building a resilient loan portfolio by prioritizing high-quality collaterals and prudent loan-to-value ratios. During the year, the average loan-to-value ratio for first mortgage was approximately 56.27%, while overall average loan-to-value ratio for subordinate mortgage was approximately 40.82% of which, average loan-to-value ratio of subordinate mortgage that the Group participated in was approximately 3.73%.

Reflecting our robust credit risk management, the charge for impairment losses recognized on loan receivables decreased from approximately HK$46.3 million to approximately HK$12.7 million, representing a decrease of approximately 72.6% or HK$33.6 million.

Pawn Loan Business

The revenue from the pawn loan business increased by approximately 12.9% to approximately HK$98.6 million in FY2026. The business’s profitability was further bolstered by a significant 73.0% increase in the gain on disposal of repossessed assets, which reached approximately HK$19.2 million as compared to approximately HK$11.1 million in FY2025. This performance was mainly attributed to the unprecedented strength of gold prices and a highly active secondary market for luxuries, particularly high-end timepieces. These factors have further solidified the pawn loan business as a resilient and strategic hedge against broader economic volatility.

During the year, the Group continued to channel resources to advertising and promotion to enhance the Group’s brand exposure. Such effort has generated demand for one-to-one pawn loan appointment services for pawn loans exceeding HK$0.1 million.

PROSPECTS

Looking ahead, the Group maintains a stance of cautious optimism regarding the global economic recovery. While macroeconomic and geopolitical uncertainties may persist, we remain dedicated to a proactive yet prudent strategy to ensure sustainable long-term growth and maximize returns for our shareholders.

Within the mortgage loan market, our strategy will be characterized by a calibrated and divergent approach. We continue to hold an optimistic outlook on the residential property segment, where we intend to capitalize on the stabilizing interest rate environment by identifying high-quality mortgage opportunities. Conversely, we maintain cautious and vigilant towards the commercial and industrial sectors. Given the structural challenges of inventory overhang and the increasing prevalence of distressed assets, the Group will exercise intensified oversight in its credit underwriting and collateral appraisal to mitigate valuation risks.

Regarding our core operations, we anticipate our pawn loan business to remain resilient, supported by a firm gold price trajectory and sustained demand for liquidity management. To further enhance operational efficiency, the Group is actively optimizing its pawn shop network. We are strategically identifying more cost-effective locations within our established service areas, aiming to relocate our pawn outlets to premises with more competitive lease terms to reduce operating overheads while maintaining our leading market presence.

Simultaneously, our strategic partnership with PACM Group remains a key driver for geographic diversification. By proactively exploring institutional credit opportunities in developed markets while maintaining rigorous investment oversight, the Group is well-positioned to navigate evolving industry dynamics and deliver stable value to all stakeholders.

Mr. Edward Chan, Chairman and CEO of the Company, said, “Global geopolitical and macroeconomic uncertainties intertwine, placing pressure on the global economic recovery and posing ongoing challenges to the local property market. In the face of a complex external environment, Oi Wah has consistently adhered to a proactive yet prudent management strategy. Our core pawn loan business has fully demonstrated its role as a strategic tool to hedge against macroeconomic fluctuations, showcasing the Group’s strong resilience amidst market challenges.

Looking forward, we will adopt a carefully calibrated differentiation strategy and continue to drive regional diversification. Under strict investment monitoring, we will actively explore business opportunities in developed markets to further expand our revenue streams and customer base, striving to deliver long-term, stable, and sustainable returns for our shareholders.”

Hashtag: #OiWah

The issuer is solely responsible for the content of this announcement.

About Oi Wah Pawnshop Credit Holdings Limited

Oi Wah is a financing service provider in Hong Kong, mainly providing short-term secured financing, including pawn loans and mortgage loans. The Group established its first pawnshop in 1975 and currently owns 10 pawnshops and one premium service center in various locations in Hong Kong. Oi Wah diversified into mortgage loan business in 2009. The Group is the first local pawn shop which successfully listed on the Main Board of The Stock Exchange of Hong Kong Limited on 12 March 2013.

During the conference, city officials reviewed the achievements of the “14th Five-Year Plan” period, noting that the progress made over the past five years has laid a solid foundation for the upcoming phase. The formulation of the new plan adhered to an open and inclusive approach, extensively incorporating feedback from various sectors of society. Following 36 rounds of revisions, the finalized document comprises 16 chapters and 77 sections, supported by 528 key projects designated for implementation.

The plan highlights five distinct features and centers on the comprehensive elevation of the city’s “Eight Qualities,” covering industrial development, innovation capacity, openness, ecological environment, cultural and humanistic development, public services, governance systems, and quality of life. Relevant officials further elaborated on key priorities, including the development of a modern industrial system, science and technology innovation-driven growth, advancement of new industrialization, implementation of the rural revitalization strategy, and optimization of public welfare and well-being.

Binzhou officials emphasized that the plan is not merely a policy document, but a strategic choice and action commitment for the city’s development toward 2030. Over the next five years, Binzhou is poised to fulfill its mission of “taking the lead and shouldering greater responsibilities.” Guided by the plan, the city will continue to exert effort in enhancing urban quality, driving innovation-led transformation, and improving public well-being, thereby writing a distinctive chapter of development within China’s broader journey toward modernization.

Hashtag: #BinzhouInformationOffice

The issuer is solely responsible for the content of this announcement.

Another significant step towards the success of ICVAX®

HONG KONG SAR – Media OutReach Newswire – 27 May 2026 – Immuno Cure Group (“Immuno Cure“), headquartered at Hong Kong Science Park, is pleased to announce the inauguration of the research facility for its HIV therapeutic DNA vaccine (“ICVAX^®“) at the Center of International Innovation for Technology and Science (“CIITS”) located in Hetao, Shenzhen. The facility aims for the development and application of key technologies for the clinical research and commercialization of Immuno Cure’s ICVAX^®. ICVAX^® is developed by Immuno Cure with the aim of achieving antiretroviral therapy (“ART“)-free functional cure for HIV infection. This project is carried out in collaboration with Prof. Zhiwei CHEN, the Founding Director of the AIDS Institute of Li Ka Shing Faculty of Medicine, the University of Hong Kong (“HKU AIDS Institute“), and Prof. Hongzhou LU, President of the Third People’s Hospital of Shenzhen, in the capacity as advisors.

CIITS is a national-level achievement transformation platform co-built by Guangdong Province, Shenzhen Municipality, and Tsinghua University, and is located at the Hetao Shenzhen-Hong Kong Science and Technology Innovation Co-operation Zone (“Hetao Co-operation Zone“). It is committed to building a world’s leading major technological innovation and industrialization platform with a global perspective. It focuses on key tracks including biomedicine, high-performance materials, and artificial intelligence (AI). It aims to aggregate global innovation resources, connect with leading enterprises, and conduct organized scientific research and achievement transformation to address national major strategic needs.

Since AIDS was first identified in 1981, 40.8 million people have died from HIV infection, with over 44.1 million people living with HIV globally. While antiretroviral therapy can effectively control HIV replication, it cannot cure the disease, highlighting the critical need for immunotherapies. Designed to enhance the host’s immune response, immunotherapies aim to achieve sustained viral control without lifelong ART, ultimately leading to complete viral suppression and functional cure. Immuno Cure’s proprietary innovative HIV therapeutic DNA vaccine, ICVAX^®, induces broad-spectrum, polyfunctional virus-specific T cells to achieve the ultimate goal of ART-free functional cure of HIV infection.

Immuno Cure completed the first-in-human Phase I clinical trial of ICVAX^® in November 2024, demonstrating excellent safety and promising immunogenicity. Two multi-center Phase II clinical trials—randomized, double-blind, and placebo-controlled—are scheduled to launch in Q2-2026 to evaluate the vaccine’s mechanism of action and efficacy. The trials will be conducted at Prince of Wales Hospital in Hong Kong, as well as eight top-tier hospitals in China, including the Shenzhen Third People’s Hospital, Beijing Ditan Hospital Affiliated to Capital Medical University, Beijing Youan Hospital affiliated to Capital Medical University, the Eighth People’s Hospital of Guangzhou, the Second People’s Hospital of Tianjin, the Sixth People’s Hospital of Zhengzhou, Chengdu Public Health Clinical Medical Center, and Chongqing Public Health Medical Center.

Notably, standardized testing systems for evaluating immunological and virological indicators are crucial for HIV vaccine clinical trials. However, the lack of domestic standard operating procedures (SOPs) for infectious samples in clinical trials hinders the clinical development and regulatory approval of novel infectious disease therapies like ICVAX^®. The mission of this research facility at CIITS is to establish an internationally aligned standardized clinical testing system for T-cell immunogenicity and viral reservoirs, as well as identify core biomarkers associated with vaccine efficacy — filling a domestic technical gap. Immuno Cure will offer the ICVAX^® Phase II clinical trial to facilitate the development of this standardized precision testing method for clinical sample analysis.

Dr. Xia JIN, CEO of Immuno Cure, stated, “I am delighted to be appointed to lead this key project of CIITS. I would also like to thank CIITS for the fully fitted modern laboratory space and the RMB10.0m funding support for this 2-year initial phase. My whole scientific team is committed to contributing diligently to the success of this project. I have no doubt that the development of a standardised testing regime would not only enhance the quality of our clinical trials for ICVAX^® but would also eventually be adopted as industry and national standards for the clinical translation of medicine for HIV/AIDS and other infectious diseases.

Renchen LIU, Executive Deputy Dean of Research Institute of Tsinghua University in Shenzhen and Director of CIITS, stated, “Warmest congratulations on the inauguration of the research facility for ICVAX^® at the CIITS. In the future, CIITS will continue to leverage its platform resources to implement full-chain incubation services. Project managers will provide service support throughout the entire project period, ensuring the smooth progress of the project through resource integration, talent recruitment and development, clinical collaboration, and achievement transformation. These efforts will safeguard the steady progress of the project.”

As the project advances, Immuno Cure’s ICVAX^® is positioned to become the world’s first therapeutic DNA vaccine to deliver an ART-free functional cure for HIV infection, bringing new hope to people currently living with HIV. In parallel, the standardized testing platform and collaborative innovation model developed through this effort will provide a scalable, replicable blueprint for R&D of novel therapies targeting other major infectious diseases. Together, these outcomes will strengthen the global competitiveness of biomedicine development in GBA and contribute to the development of national biosecurity capabilities and a more resilient public health system.

Hashtag: #ImmunoCure

https://immunocure.hk
https://www.linkedin.com/company/immuno-cure

The issuer is solely responsible for the content of this announcement.

About the Center of International Innovation for Technology and Science (“CIITS”)

Center of International Innovation for Technology and Science (CIITS), as the international headquarter of the Greater Bay Area National Center of Technology Innovation (GBA NCTI), is operated by Research Institute of Tsinghua University in Shenzhen (RITS). CIITS actively promotes the commercialization of technology and scientific advances with overseas and domestic innovation institutions and teams, as well as industry partners, focusing on areas such as biomedicine, advanced materials and artificial intelligence.

To learn more about CIITS, please follow the WeChat official account: gh_425f503135d5

About Immuno Cure

Immuno Cure is a clinical-stage biotechnology group headquartered at Hong Kong Science Park. Immuno Cure is committed to the R&D of innovative DNA vaccines and antibody immunotherapies for infectious diseases, inflammations, and cancers. Immuno Cure possesses two technologies: the “PD-1 Enhanced DNA Vaccine Platform” and the “Anti-Δ42PD1 Antibody”.

To learn more about Immuno Cure, please visit: www.immunocure.hk